Heterogeneity and disease invasion

Overview

Whether a disease invades a population after an introduction is fundamentally a stochastic process. We have learned that individual-level variation can:

  • reduce the probability of invasion by increasing the effects of stochasticity
  • increase the probability of invasion by increasing the basic reproductive number as a disease invades

The group will make a simple model of these two countervailing effects and investigate how they work and when one is more important than the other.

It is expected that the group will rely mostly on simulations, but it is worth noting that this is a topic that could likely support mathematical exploration as well.

Things to consider

  • When deciding on your interest in this project, please consider the following:
    • The faculty member leading this project is based in Ontario (six hours earlier than Cape Town).
  • This group is recommended for:
    • Participants interested in super-spreading and heterogeneity
    • Participants interested in learning about stochastic simulation
    • [Optionally] participants interested in mathematical approximations and results
    • Participants interested in learning to use git and GitHub for collaborative code development
  • This group will have the opportunity to engage in the following:
    • Literature review about host jumps and disease establishment
    • Coding and analyzing stochastic simulations

Data

  • This project will probably be simulation-based

Resources

References